Longevity, Interpreted.

A scientist’s reading of the evidence

Most longevity claims travel further than their evidence. Each week I read the primary literature, the trial registries and the regulators, and report how far: what was shown, at what stage, and what it does not yet support.

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Health by age

Most longevity news is early. These plain guides cover what is already proven, stage by stage, with Indian sources first.


The latest issue · 19–25 October 2026

Business
  • Regeneron says trevogrumab preserved lean and muscle mass during GLP-1 weight loss
  • Longevity clinic leaders called for standardised care as health systems open their own programmes
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Healthspan
  • Products sold as cat's claw contained undeclared kratom alkaloids and tianeptine
  • Regeneron says trevogrumab preserved muscle mass during GLP-1 weight loss, and nobody reported strength
  • A PhenoAge clock reading rose with tumour stage, and may be tracking cancer rather than aging
  • THE THREAD THIS WEEK
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Sucheendra Kumar Palaniappan
Edited by
Sucheendra Kumar Palaniappan

Scientist working at the intersection of computation, biology and medicine. Longevity, Interpreted. exists to understand the evidence, not sell an intervention.

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Mice are not humans · Biomarkers are not outcomes · Funding is not validation
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